Modulation of the microbiota by oral antibiotics treats immunoglobulin A nephropathy in humanized mice.

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作者： Jonathan M,Chemouny ^[1] ; Patrick J,Gleeson ^[2] ; Lilia,Abbad ^[3] ; Gabriella,Lauriero ^[4] ; Erwan,Boedec ^[5] ; Karine,Le Roux ^[1] ; Céline,Monot ^[2] ; Maxime,Bredel ^[3] ; Julie,Bex-Coudrat ^[1] ; Aurélie,Sannier ^[2] ; Eric,Daugas ^[3] ; Francois,Vrtovsnik ^[1] ; Loreto,Gesualdo ^[2] ; Marion,Leclerc ^[3] ; Laureline,Berthelot ^[6] ; Sanae,Ben Mkaddem ^[1] ; Patricia,Lepage ^[2] ; Renato C,Monteiro ^[3]

作者单位： INSERM 1149, Center for Research on Inflammation (CRI), Paris, France. ^[1] CNRS ERL8252, Paris, France. ^[2] Inflamex Laboratory of Excellence, School of Medicine, Paris Diderot University, Sorbonne Paris Cité, Paris, France. ^[3] Nephrology Department, Bichat-Claude Bernard Hospital, AP-HP, DHU Fire, Paris, France. ^[4] Institut Micalis, INRA, AgroParisTech, University Paris-Saclay, Jouy-en-Josas, France. ^[5] Department of Emergency and Organ Transplantation, Division of Nephrology, Dialysis, and Transplantation, University of Bari, Bari, Italy. ^[6] Pathology Department, Bichat-Claude Bernard Hospital, AP-HP, DHU Fire, Paris, France. ^[7] Hemato-Immunology Department, UF Immunity Dysfunctions, Bichat-Claude Bernard Hospital, AP-HP, DHU Fire, Paris, France. ^[8]

关键词 GALT IgA IgA nephropathy antibiotics gut microbiome