首页> Methods in enzymology> Challenges in the Structural-Functional Characterization of Multidomain, Partially Disordered Proteins CBP and p300: Preparing Native Proteins and Developing Nanobody Tools.

Challenges in the Structural-Functional Characterization of Multidomain, Partially Disordered Proteins CBP and p300: Preparing Native Proteins and Developing Nanobody Tools.

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第一作者： Angela,Bekesi

第一单位： VIB-VUB Center for Structural Biology (CSB), VIB, Brussels, Belgium; Structural Biology Brussels (SBB), Vrije Universiteit Brussel (VUB), Brussels, Belgium.

作者： Angela,Bekesi ^[1] ; Sara,Abdellaoui ^[1] ; Natalie,Holroyd ^[2] ; Wouter,Van Delm ^[3] ; Els,Pardon ^[1] ; Jarne,Pauwels ^[4] ; Kris,Gevaert ^[4] ; Jan,Steyaert ^[1] ; Stefaan,Derveaux ^[3] ; Antoni,Borysik ^[2] ; Peter,Tompa ^[5]

作者单位： VIB-VUB Center for Structural Biology (CSB), VIB, Brussels, Belgium; Structural Biology Brussels (SBB), Vrije Universiteit Brussel (VUB), Brussels, Belgium. ^[1] King's College London, Department of Chemistry, London, United Kingdom. ^[2] VIB Nucleomics Core, VIB, Leuven, Belgium. ^[3] VIB Center for Medical Biotechnology, VIB, Ghent, Belgium; Department of Biochemistry, Ghent University, Ghent, Belgium. ^[4] VIB-VUB Center for Structural Biology (CSB), VIB, Brussels, Belgium; Structural Biology Brussels (SBB), Vrije Universiteit Brussel (VUB), Brussels, Belgium; Institute of Enzymology, Research Centre for Natural Sciences of the Hungarian Academy of Sciences, Budapest, Hungary. Electronic address: peter.tompa@vub.vib.be. ^[5]

关键词 CBP Crystallization aid HAT Histone acetyltransferase Intrinsic protein disorder KIX Molecular label Nanobody p300