Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of <i>N</i>-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.

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第一作者： Santosh Kumar,Adla

第一单位： Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.

作者： Santosh Kumar,Adla ^[1] ; Barbora,Slavikova ^[1] ; Hana,Chodounska ^[1] ; Vojtech,Vyklicky ^[2] ; Marek,Ladislav ^[2] ; Pavla,Hubalkova ^[2] ; Barbora,Krausova ^[2] ; Tereza,Smejkalova ^[2] ; Michaela,Nekardova ^[1] ; Marketa,Smidkova ^[3] ; Lenka,Monincova ^[1] ; Radko,Soucek ^[1] ; Ladislav,Vyklicky ^[1] ; Eva,Kudova ^[2]

作者单位： Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia. ^[1] Institute of Physiology, Czech Academy of Sciences, Prague, Czechia. ^[2] Faculty of Mathematics and Physics, Charles University in Prague, Prague, Czechia. ^[3]

关键词 NMDA receptor amide neurosteroid plasma stability structure-activity relationship

DOI 10.3389/fphar.2018.01299

PMID 30483134

发布时间 2020-09-30

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Frontiers in pharmacology

2018年9卷

1299页

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Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of <i>N</i>-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.

Frontiers in pharmacology

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Frontiers in pharmacology

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Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of <i>N</i>-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.

Frontiers in pharmacology

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Frontiers in pharmacology

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