DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.-论文-万方医学网

作者： Ryoichi,Matsunuma ^[1] ; Doug W,Chan ^[2] ; Beom-Jun,Kim ^[3] ; Purba,Singh ^[1] ; Airi,Han ^[1] ; Alexander B,Saltzman ^[1] ; Chonghui,Cheng ^[1] ; Jonathan T,Lei ^[4] ; Junkai,Wang ^[5] ; Leonardo,Roberto da Silva ^[1] ; Ergun,Sahin ^[6] ; Mei,Leng ^[1] ; Cheng,Fan ^[7] ; Charles M,Perou ^[1] ; Anna,Malovannaya ^[8] ; Matthew J,Ellis ^[1]

作者单位： Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030. ^[1] First Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan. ^[2] Department of Medical Oncology, Hamamatsu Oncology Center, Hamamatsu, Shizuoka 430-0929, Japan. ^[3] Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 220-701, Korea. ^[4] Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030. ^[5] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030. ^[6] Interdepartmental Graduate Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX 77030. ^[7] Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030. ^[8] Department of Obstetrics and Gynecology, Faculty of Medical Science, State University of Campinas-UNICAMP, Campinas, São Paulo 13083-970, Brazil. ^[9] Department of Physiology and Biophysics, Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030. ^[10] Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599. ^[11] Mass Spectrometry Proteomics Core, Baylor College of Medicine, Houston, TX 77030. ^[12] Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030; Matthew.Ellis@bcm.edu. ^[13]

主题词动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);壳牢素类(Claudins);上皮-间质转化(Epithelial-Mesenchymal Transition);反馈, 生理(Feedback, Physiological);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲低技术(Gene Knockdown Techniques);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);有丝分裂(Mitosis);肌蛋白质类(Muscle Proteins);核蛋白质类(Nuclear Proteins);磷酰化(Phosphorylation);蛋白质组学(Proteomics);阻遏蛋白质类(Repressor Proteins);信号传导(Signal Transduction);波形蛋白(Vimentin);p21活化激酶类(p21-Activated Kinases)

DOI 10.1073/pnas.1810598115

PMID 30498031

发布时间 2024-07-02

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DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.

Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

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DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.

Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

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