Systems analysis of phosphorylation-regulated Bcl-2 interactions establishes a model to reconcile the controversy over the significance of Bcl-2 phosphorylation.
第一作者:
Ting,Song
第一单位:
State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.
作者:
主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞增殖(Cell Proliferation);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);依托泊甙(Etoposide);人类(Humans);动力学(Kinetics);配体(Ligands);模型, 生物学(Models, Biological);磷酰化(Phosphorylation);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);磺胺类(Sulfonamides);表面等离激元(Surface Plasmon Resonance);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1111/bph.14555
PMID
30500985
发布时间
2024-06-03
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