Defining Changes in the Spatial Distribution and Composition of Brain Lipids in the Shiverer and Cuprizone Mouse Models of Myelin Disease.

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作者： Rajanikanth J,Maganti ^[1] ; Xiaoping L,Hronowski ^[2] ; Robert W,Dunstan ^[1] ; Brian T,Wipke ^[1] ; Xueli,Zhang ^[3] ; Luke,Jandreski ^[1] ; Stefan,Hamann ^[1] ; Peter,Juhasz ^[1]

作者单位： Biogen, Cambridge, Massachusetts. ^[1] Moderna Therapeutics, Cambridge, Massachusetts. ^[2] AbbVie, Worcester, Massachusetts. ^[3]

关键词 brain cuprizone electrospray ionization mass spectrometry matrix-assisted laser desorption ionization myelin shiverer

主题词动物(Animals);神经酰胺类(Ceramides);胼胝体(Corpus Callosum);铜宗(Cuprizone);脱髓鞘疾病(Demyelinating Diseases);疾病模型, 动物(Disease Models, Animal);免疫组织化学(Immunohistochemistry);脂类代谢(Lipid Metabolism);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);髓鞘(Myelin Sheath);磷脂酰胆碱类(Phosphatidylcholines);光谱法, 质量, 电喷雾电离(Spectrometry, Mass, Electrospray Ionization);光谱法, 质量, 基质辅助激光解吸电离(Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization);硫糖神经鞘类脂(Sulfoglycosphingolipids)

DOI 10.1369/0022155418815860

PMID 30501365

发布时间 2020-03-09

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The journal of histochemistry and cytochemistry

2019年67卷3期

203-219页

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Defining Changes in the Spatial Distribution and Composition of Brain Lipids in the Shiverer and Cuprizone Mouse Models of Myelin Disease.

The journal of histochemistry and cytochemistry

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The journal of histochemistry and cytochemistry

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Defining Changes in the Spatial Distribution and Composition of Brain Lipids in the Shiverer and Cuprizone Mouse Models of Myelin Disease.

The journal of histochemistry and cytochemistry

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The journal of histochemistry and cytochemistry

相关期刊

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