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Comparative proteomics identified immune response proteins involved in response to vaccination with heat-inactivated Mycobacterium bovis and mycobacterial challenge in cattle.

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第一作者： Vladimir,Lopez

第一单位： SaBio, Instituto de Investigación en Recursos Cinegéticos IREC CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain.

作者： Vladimir,Lopez ^[1] ; Elisabeth,van der Heijden ^[2] ; Margarita,Villar ^[1] ; Anita,Michel ^[3] ; Pilar,Alberdi ^[1] ; Christian,Gortázar ^[1] ; Victor,Rutten ^[4] ; José,de la Fuente ^[5]

作者单位： SaBio, Instituto de Investigación en Recursos Cinegéticos IREC CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain. ^[1] Division of Immunology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL, Utrecht, the Netherlands; Department of Veterinary Tropical Diseases, Bovine Tuberculosis and Brucellosis Research Programme, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, Pretoria, South Africa. Electronic address: e.m.d.l.vanderheijden@uu.nl. ^[2] Department of Veterinary Tropical Diseases, Bovine Tuberculosis and Brucellosis Research Programme, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, Pretoria, South Africa; Research Associate of the National Zoological Gardens of South Africa, 232 Boom St, Daspoort 319-Jr, 0001, Pretoria, South Africa. ^[3] Division of Immunology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL, Utrecht, the Netherlands; Department of Veterinary Tropical Diseases, Bovine Tuberculosis and Brucellosis Research Programme, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, Pretoria, South Africa. ^[4] SaBio, Instituto de Investigación en Recursos Cinegéticos IREC CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain; Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA. ^[5]

关键词 Bovine tuberculosis Comparative proteomics Heat-inactivated M. bovisvaccine Immune response proteins Mycobacterium bovis Vaccination