Phenamacril is a reversible and noncompetitive inhibitor of <i>Fusarium</i> class I myosin.

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作者： Rasmus D,Wollenberg ^[1] ; Manuel H,Taft ^[2] ; Sven,Giese ^[2] ; Claudia,Thiel ^[3] ; Zoltán,Balázs ^[1] ; Henriette,Giese ^[1] ; Dietmar J,Manstein ^[4] ; Teis E,Sondergaard ^[5]

作者单位： Department of Chemistry and Bioscience, Aalborg University, DK-9220 Aalborg, Denmark. ^[1] Institute for Biophysical Chemistry, OE4350, Hannover Medical School, 30623 Hannover, Germany. ^[2] Division of Structural Biochemistry, OE8830, Hannover Medical School, 30623 Hannover, Germany. ^[3] Institute for Biophysical Chemistry, OE4350, Hannover Medical School, 30623 Hannover, Germany; Division of Structural Biochemistry, OE8830, Hannover Medical School, 30623 Hannover, Germany. Electronic address: manstein.dietmar@mh-hannover.de. ^[4] Department of Chemistry and Bioscience, Aalborg University, DK-9220 Aalborg, Denmark. Electronic address: tes@bio.aau.dk. ^[5]

关键词 ATPase allosteric regulation cytoskeleton fungi fungicide inhibition mechanism inhibitor motor protein myosin phenamacril

主题词杀真菌剂, 工业(Fungicides, Industrial);镰刀菌属(Fusarium);基因表达调控, 真菌(Gene Expression Regulation, Fungal);肌球蛋白Ⅰ型(Myosin Type I);蛋白质构象(Protein Conformation);种特异性(Species Specificity)

DOI 10.1074/jbc.RA118.005408

PMID 30504222

发布时间 2023-10-05

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