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Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections.

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作者单位: JRG Translational Hematology of Congenital Diseases, Hannover Medical School, Hannover, Germany. [1] Institute of Experimental Hematology, REBIRTH Cluster of Excellence, Hannover Medical School, 30625, Hannover, Germany. [2] Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiothoracic, Transplantation and Vascular Surgery, REBIRTH Cluster of Excellence, Hannover Medical School, 30625, Hannover, Germany. [3] Department of Stem Cell Biology, Novo Nordisk A/S, 2760, Maaloev, Denmark. [4] RG Reprogramming and Gene Therapy, Hannover Medical School, 30625, Hannover, Germany. [5] Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), REBIRTH Cluster-of Excellence, 30625, Hannover, Germany. [6] Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), German Center for Lung Research, 30625, Hannover, Germany. [7] Clinical Research Group 'Cystic Fibrosis', Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, 30625, Hannover, Germany. [8] Institute for Pathology, Hannover Medical School, 30625, Hannover, Germany. [9] Institute of Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Hannover, Germany. [10] Institute for Transfusion Medicine, Hannover Medical School, 30625, Hannover, Germany. [11] Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02215, USA. [12] JRG Translational Hematology of Congenital Diseases, Hannover Medical School, Hannover, Germany. lachmann.nico@mh-hannover.de. [13] Institute of Experimental Hematology, REBIRTH Cluster of Excellence, Hannover Medical School, 30625, Hannover, Germany. lachmann.nico@mh-hannover.de. [14]
DOI 10.1038/s41467-018-07570-7
PMID 30504915
发布时间 2022-01-14
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