Alpha-naphthoflavone induces apoptosis through endoplasmic reticulum stress via c-Src-, ROS-, MAPKs-, and arylhydrocarbon receptor-dependent pathways in HT22 hippocampal neuronal cells.

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作者： Ah-Ran,Yu ^[1] ; Yeon Ju,Jeong ^[1] ; Chi Yeon,Hwang ^[1] ; Kyung-Sik,Yoon ^[2] ; Wonchae,Choe ^[2] ; Joohun,Ha ^[2] ; Sung Soo,Kim ^[2] ; Youngmi Kim,Pak ^[3] ; Eui-Ju,Yeo ^[4] ; Insug,Kang ^[5]

作者单位： Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea. ^[1] Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea; Department of Biochemistry and Molecular Biology, School of Medicine, Biomedical Science Institute, Kyung Hee University, Seoul, 02447, Republic of Korea. ^[2] Department of Physiology, School of Medicine, Biomedical Science Institute, Kyung Hee University, Seoul, 02447, Republic of Korea. ^[3] Department of Biochemistry, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea. Electronic address: euiju@gachon.ac.kr. ^[4] Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea; Department of Biochemistry and Molecular Biology, School of Medicine, Biomedical Science Institute, Kyung Hee University, Seoul, 02447, Republic of Korea. Electronic address: iskang@khu.ac.kr. ^[5]

关键词 Apoptosis Aryl hydrocarbon receptor modulator ER stress HT22 hippocampal neuronal cells α-Naphthoflavone