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Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status.

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第一作者： L,Bramasole

第一单位： Department of Human Biology, The Faculty of Natural Sciences, University of Haifa, Haifa 3190500, Israel; Department of Biology and Environment, The Faculty of Natural Sciences, University of Haifa at Oranim, Tivon 3600600, Israel.

作者： L,Bramasole ^[1] ; A,Sinha ^[2] ; S,Gurevich ^[3] ; M,Radzinski ^[4] ; Y,Klein ^[2] ; N,Panat ^[2] ; E,Gefen ^[2] ; T,Rinaldi ^[5] ; D,Jimenez-Morales ^[6] ; J,Johnson ^[6] ; N J,Krogan ^[6] ; N,Reis ^[3] ; D,Reichmann ^[4] ; M H,Glickman ^[3] ; E,Pick ^[7]

作者单位： Department of Human Biology, The Faculty of Natural Sciences, University of Haifa, Haifa 3190500, Israel; Department of Biology and Environment, The Faculty of Natural Sciences, University of Haifa at Oranim, Tivon 3600600, Israel. ^[1] Department of Biology and Environment, The Faculty of Natural Sciences, University of Haifa at Oranim, Tivon 3600600, Israel. ^[2] Department of Biology, Technion-Israel Institute of Technology, 3200000 Haifa, Israel. ^[3] Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, Safra Campus Givat Ram, The Hebrew University of Jerusalem, Jerusalem 9190400, Israel. ^[4] Department of Biology and Biotechnology, University of Rome ''La Sapienza'', Rome 00185, Italy. ^[5] Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA. ^[6] Department of Human Biology, The Faculty of Natural Sciences, University of Haifa, Haifa 3190500, Israel; Department of Biology and Environment, The Faculty of Natural Sciences, University of Haifa at Oranim, Tivon 3600600, Israel. Electronic address: elahpic@research.haifa.ac.il. ^[7]

关键词 26S proteasome Mitochondria NEDD8/Rub1 Rpn11 Thiol switch Ubiquitin