首页> Antimicrobial agents and chemotherapy> Is One Sample Enough? β-Lactam Target Attainment and Penetration into Epithelial Lining Fluid Based on Multiple Bronchoalveolar Lavage Sampling Time Points in a Swine Pneumonia Model.

Is One Sample Enough? β-Lactam Target Attainment and Penetration into Epithelial Lining Fluid Based on Multiple Bronchoalveolar Lavage Sampling Time Points in a Swine Pneumonia Model.

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第一作者： Ana,Motos

第一单位： Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA.;Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Clinic, Barcelona, Spain.

作者： Ana,Motos ^[1] ; Joseph L,Kuti ^[2] ; Gianluigi,Li Bassi ^[3] ; Antoni,Torres ^[3] ; David P,Nicolau ^[4]

作者单位： Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA.;Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Clinic, Barcelona, Spain. ^[1] Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA. ^[2] Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Clinic, Barcelona, Spain.;Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.;University of Barcelona, Barcelona, Spain. ^[3] Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA david.nicolau@hhchealth.org.;Division of Infectious Diseases, Hartford Hospital, Hartford, Connecticut, USA. ^[4]

关键词 BAL sampling Monte Carlo simulation pneumonia