Tetraspanin 1 promotes epithelial-to-mesenchymal transition and metastasis of cholangiocarcinoma via PI3K/AKT signaling.

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作者： Yan,Wang ^[1] ; Yingjian,Liang ^[1] ; Guangchao,Yang ^[1] ; Yaliang,Lan ^[1] ; Jihua,Han ^[1] ; Jiabei,Wang ^[1] ; Dalong,Yin ^[1] ; Ruipeng,Song ^[1] ; Tongsen,Zheng ^[2] ; Shugeng,Zhang ^[1] ; Shangha,Pan ^[1] ; Xirui,Liu ^[1] ; Mingxi,Zhu ^[1] ; Yao,Liu ^[1] ; Yifeng,Cui ^[1] ; Fanzheng,Meng ^[1] ; Bo,Zhang ^[1] ; Shuhang,Liang ^[1] ; Hongrui,Guo ^[1] ; Yufeng,Liu ^[1] ; Md Khaled,Hassan ^[1] ; Lianxin,Liu ^[3]

作者单位： Department of Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China. ^[1] Department of Gastrointestinal Medical Oncology, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang, China. ^[2] Department of Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China. LiuLX@ems.hrbmu.edu.cn. ^[3] Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, China. LiuLX@ems.hrbmu.edu.cn. ^[4]

关键词 Cholangiocarcinoma Epithelial-to-mesenchymal transition Integrin α6β1 MicroRNA-194-5p Tetraspanin 1