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首页> BMC genetics> Polymorphisms of HOMER1 gene are associated with piglet splay leg syndrome and one significant SNP can affect its intronic promoter activity in vitro.

Polymorphisms of HOMER1 gene are associated with piglet splay leg syndrome and one significant SNP can affect its intronic promoter activity in vitro.

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作者： Sutong,Xu ^[1] ; Xingjie,Hao ^[1] ; Min,Zhang ^[2] ; Kai,Wang ^[1] ; Shuaifeng,Li ^[1] ; Xing,Chen ^[1] ; Liaohan,Yang ^[3] ; Lin,Hu ^[1] ; Shujun,Zhang ^[1]

作者单位： Key Lab of Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan, 430070, Hubei, China. ^[1] Department of Epidemiology and Biostatistics, Key Laboratory for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, China. ^[2] Institute of Animal Husbandry and Veterinary, Wuhan Academy of Agricultural Science, Wuhan, 430208, Hubei, China. ^[3] Key Lab of Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan, 430070, Hubei, China. marywood@163.com. ^[4]

关键词 HOMER1 Intronic promoter Piglet splay leg SNP

主题词 5'非翻译区(5' Untranslated Regions);等位基因(Alleles);动物(Animals);芳香烃受体核转位子(Aryl Hydrocarbon Receptor Nuclear Translocator);结合部位(Binding Sites);细胞系(Cell Line);全基因组关联研究(Genome-Wide Association Study);基因型(Genotype);内含子(Introns);连锁不平衡(Linkage Disequilibrium);多态性, 单核苷酸(Polymorphism, Single Nucleotide);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);猪(Swine);猪疾病(Swine Diseases)

DOI 10.1186/s12863-018-0701-0

PMID 30526478

发布时间 2024-04-05

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BMC genetics

BMC genetics

2018年19卷1期

110页

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