Highly efficient 5' capping of mitochondrial RNA with NAD<sup>+</sup> and NADH by yeast and human mitochondrial RNA polymerase.

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作者： Jeremy G,Bird ^[1] ; Urmimala,Basu ^[2] ; David,Kuster ^[3] ; Aparna,Ramachandran ^[4] ; Ewa,Grudzien-Nogalska ^[1] ; Atif,Towheed ^[2] ; Douglas C,Wallace ^[5] ; Megerditch,Kiledjian ^[3] ; Dmitry,Temiakov ^[6] ; Smita S,Patel ^[7] ; Richard H,Ebright ^[7] ; Bryce E,Nickels ^[8]

作者单位： Department of Genetics and Waksman Institute, Rutgers University, United States. ^[1] Department of Chemistry and Waksman Institute, Rutgers University, United States. ^[2] Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, United States. ^[3] Biochemistry PhD Program, School of Graduate Studies, Rutgers University, United States. ^[4] Biochemistry Center Heidelberg, Heidelberg University, Germany. ^[5] Department of Cell Biology and Neuroscience, Rutgers University, United States. ^[6] Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, United States. ^[7] Department of Pediatrics, Division of Human Genetics, The Children's Hospital of Philadelphia, Perelman School of Medicine, United States. ^[8] Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, United States. ^[9]

关键词 E. coli RNA capping RNA polymerase S. cerevisiae biochemistry chemical biology chromosomes gene expression human metabolism mitochondria non-canonical initiating nucleotide transcription initiation