第一作者:
Seung Hoan,Choi
第一单位:
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
作者:
Seung Hoan,Choi [1]
;
Lu-Chen,Weng [2]
;
Carolina,Roselli [1]
;
Honghuang,Lin [3]
;
Christopher M,Haggerty [4]
;
M Benjamin,Shoemaker [5]
;
John,Barnard [6]
;
Dan E,Arking [7]
;
Daniel I,Chasman [8]
;
Christine M,Albert [9]
;
Mark,Chaffin [1]
;
Nathan R,Tucker [2]
;
Jonathan D,Smith [10]
;
Namrata,Gupta [1]
;
Stacey,Gabriel [1]
;
Lauren,Margolin [1]
;
Marisa A,Shea [11]
;
Christian M,Shaffer [5]
;
Zachary T,Yoneda [5]
;
Eric,Boerwinkle [12]
;
Nicholas L,Smith [13]
;
Edwin K,Silverman [14]
;
Susan,Redline [15]
;
Ramachandran S,Vasan [16]
;
Esteban G,Burchard [17]
;
Stephanie M,Gogarten [18]
;
Cecelia,Laurie [18]
;
Thomas W,Blackwell [19]
;
Gonçalo,Abecasis [19]
;
David J,Carey [20]
;
Brandon K,Fornwalt [4]
;
Diane T,Smelser [20]
;
Aris,Baras [21]
;
Frederick E,Dewey [21]
;
Cashell E,Jaquish [22]
;
George J,Papanicolaou [22]
;
Nona,Sotoodehnia [23]
;
David R,Van Wagoner [24]
;
Bruce M,Psaty [25]
;
Sekar,Kathiresan [1]
;
Dawood,Darbar [26]
;
Alvaro,Alonso [27]
;
Susan R,Heckbert [28]
;
Mina K,Chung [29]
;
Dan M,Roden [5]
;
Emelia J,Benjamin [30]
;
Michael F,Murray [31]
;
Kathryn L,Lunetta [32]
;
Steven A,Lubitz [33]
;
Patrick T,Ellinor [33]
;
DiscovEHR study and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
作者单位:
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
[1]
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.;Cardiovascular Research Center, Massachusetts General Hospital, Boston.
[2]
National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.;Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
[3]
Department of Imaging Science and Innovation, Geisinger, Danville, Pennsylvania.
[4]
Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.
[5]
Departments of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
[6]
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
[7]
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.;Divisions of Preventive Medicine and Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
[8]
Divisions of Preventive and Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
[9]
Departments of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, Ohio.
[10]
Cardiovascular Research Center, Massachusetts General Hospital, Boston.
[11]
Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston.
[12]
Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle.
[13]
Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
[14]
Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts.
[15]
National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.
[16]
Department of Bioengineering, School of Pharmacy, University of California, San Francisco.
[17]
Department of Biostatistics, University of Washington, Seattle.
[18]
Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor.
[19]
Department of Molecular and Functional Genomics, Geisinger, Danville, Pennsylvania.
[20]
Regeneron Genetics Center, Tarrytown, New York.
[21]
Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
[22]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle.
[23]
Departments of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio.
[24]
Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle.;Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle.;Kaiser Permanente Washington Health Research Institute, Seattle, Washington.;Department of Health Services, University of Washington, Seattle.
[25]
Division of Cardiology, Department of Medicine, University of Illinois, Chicago.
[26]
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
[27]
Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle.;Kaiser Permanente Washington Health Research Institute, Seattle, Washington.
[28]
Departments of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio.
[29]
National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.;Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.;Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
[30]
Genomic Medicine Institute, Geisinger, Danville, Pennsylvania.
[31]
National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.;Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
[32]
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.;Cardiovascular Research Center, Massachusetts General Hospital, Boston.;Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston.
[33]
主题词
成年人(Adult);发病年龄(Age of Onset);心房颤动(Atrial Fibrillation);病例对照研究(Case-Control Studies);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);杂合子(Heterozygote);人类(Humans);男(雄)性(Male);中年人(Middle Aged);质量控制(Quality Control)
DOI
10.1001/jama.2018.18179
PMID
30535219
发布时间
2024-09-22
- 浏览6

JAMA
JAMA
2354-2364页
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