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Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.

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第一作者: Seung Hoan,Choi
第一单位: Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
作者单位: Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts. [1] Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.;Cardiovascular Research Center, Massachusetts General Hospital, Boston. [2] National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.;Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts. [3] Department of Imaging Science and Innovation, Geisinger, Danville, Pennsylvania. [4] Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee. [5] Departments of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio. [6] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. [7] Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.;Divisions of Preventive Medicine and Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. [8] Divisions of Preventive and Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. [9] Departments of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, Ohio. [10] Cardiovascular Research Center, Massachusetts General Hospital, Boston. [11] Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston. [12] Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle. [13] Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. [14] Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts. [15] National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts. [16] Department of Bioengineering, School of Pharmacy, University of California, San Francisco. [17] Department of Biostatistics, University of Washington, Seattle. [18] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor. [19] Department of Molecular and Functional Genomics, Geisinger, Danville, Pennsylvania. [20] Regeneron Genetics Center, Tarrytown, New York. [21] Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland. [22] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle. [23] Departments of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio. [24] Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle.;Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle.;Kaiser Permanente Washington Health Research Institute, Seattle, Washington.;Department of Health Services, University of Washington, Seattle. [25] Division of Cardiology, Department of Medicine, University of Illinois, Chicago. [26] Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia. [27] Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle.;Kaiser Permanente Washington Health Research Institute, Seattle, Washington. [28] Departments of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio. [29] National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.;Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.;Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts. [30] Genomic Medicine Institute, Geisinger, Danville, Pennsylvania. [31] National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham, Massachusetts.;Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts. [32] Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.;Cardiovascular Research Center, Massachusetts General Hospital, Boston.;Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston. [33]
DOI 10.1001/jama.2018.18179
PMID 30535219
发布时间 2024-09-22
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2018年320卷22期

2354-2364页

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