Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis.-论文-万方医学网

作者： Wenli,Liu ^[1] ; Chenji,Ye ^[1] ; Qian,Cheng ^[1] ; Xuejiao,Zhang ^[1] ; Liu,Yao ^[1] ; Qi,Li ^[1] ; Jing,Huang ^[1] ; Yajin,Liu ^[1] ; Zhengsheng,Zou ^[2] ; Hua,Wang ^[3] ; Jun,Yan ^[4] ; Yi,Zhu ^[1] ; Chunjiong,Wang ^[5] ; Ding,Ai ^[6]

作者单位： Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China. ^[1] The Center for Non-infectious Liver Diseases, Beijing 302 Military Hospital, Beijing, China. ^[2] Department of Oncology, the First Affiliated Hospital, Institute for Liver Diseases of Anhui Medical University, Hefei, China. ^[3] Department of Pathology, Tianjin First Center Hospital, Tianjin, China. ^[4] Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China. Electronic address: wangchunjiong@126.com. ^[5] Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China. Electronic address: edin2000cn@163.com. ^[6]

主题词动物(Animals);细胞凋亡(Apoptosis);钙(Calcium);胆固醇(Cholesterol);胆碱(Choline);膳食(Diet);疾病恶化(Disease Progression);动力蛋白质类(Dynamins);摄食行为(Feeding Behavior);果糖(Fructose);GTP磷酸水解酶类(GTP Phosphohydrolases);基因缺失(Gene Deletion);肝细胞(Hepatocytes);人类(Humans);炎症(Inflammation);脂解作用(Lipolysis);肝(Liver);溶酶体(Lysosomes);巨噬细胞, 腹膜(Macrophages, Peritoneal);男(雄)性(Male);甲硫氨酸(Methionine);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);棕榈酸盐类(Palmitates);吞噬体(Phagosomes);磷酰化(Phosphorylation);磷酸丝氨酸(Phosphoserine)

DOI 10.1016/j.jcmgh.2018.09.011

PMID 30539788

发布时间 2024-11-26

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Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis.

Cellular and molecular gastroenterology and hepatology

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Cellular and molecular gastroenterology and hepatology

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Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis.

Cellular and molecular gastroenterology and hepatology

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Cellular and molecular gastroenterology and hepatology

相关期刊

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