Optimization of Quality Attributes and Atomic Force Microscopy Imaging of Reconstituted Nanodroplets in Baicalin Loaded Self-Nanoemulsifying Formulations.

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作者： Géza,Jakab ^[1] ; Viktor,Fülöp ^[2] ; Tamás,Bozó ^[3] ; Emese,Balogh ^[4] ; Miklós,Kellermayer ^[5] ; István,Antal ^[6]

作者单位： Department of Pharmaceutics, Semmelweis University; Hőgyes E. Street 7-9, Budapest 1092, Hungary. jakab.geza@pharma.semmelweis-univ.hu. ^[1] Department of Pharmaceutics, Semmelweis University; Hőgyes E. Street 7-9, Budapest 1092, Hungary. fulop.viktor@pharma.semmelweis-univ.hu. ^[2] Department of Biophysics and Radiation Biology, Semmelweis University; Tűzoltó Street 37-47, Budapest 1094, Hungary. bozo.tamas@med.semmelweis-univ.hu. ^[3] Department of Pharmaceutics, Semmelweis University; Hőgyes E. Street 7-9, Budapest 1092, Hungary. balogh.emese@pharma.semmelweis-univ.hu. ^[4] Department of Biophysics and Radiation Biology, Semmelweis University; Tűzoltó Street 37-47, Budapest 1094, Hungary. kellermayer.miklos@med.semmelweis-univ.hu. ^[5] Department of Pharmaceutics, Semmelweis University; Hőgyes E. Street 7-9, Budapest 1092, Hungary. antal.istvan@pharma.semmelweis-univ.hu. ^[6]

关键词 atomic force microscopy baicalin dynamic light scattering graphical optimization self-nanoemulsifying system solubility improvement

DOI 10.3390/pharmaceutics10040275

PMID 30551629

发布时间 2020-09-29

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