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首页> Probiotics and antimicrobial proteins> Secretory Expression of a Chimeric Peptide in Lactococcus lactis: Assessment of its Cytotoxic Activity and a Deep View on Its Interaction with Cell-Surface Glycosaminoglycans by Molecular Modeling.

Secretory Expression of a Chimeric Peptide in Lactococcus lactis: Assessment of its Cytotoxic Activity and a Deep View on Its Interaction with Cell-Surface Glycosaminoglycans by Molecular Modeling.

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作者： Abbas,Tanhaeian ^[1] ; Mahmoud Reza,Jaafari ^[2] ; Farajollah Shahriari,Ahmadi ^[3] ; Roghayyeh,Vakili-Ghartavol ^[1] ; Mohammad Hadi,Sekhavati ^[4]

作者单位： Department of Biotechnology and Plant Breeding, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran. ^[1] Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. ^[2] Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. ^[3] Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. ^[4] Department of Animal Sciences, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran. Sekhavati@um.ac.ir. ^[5]

关键词 Cytotoxic activity Glycosaminoglycans Lactococcus lactis Molecular dynamic simulation P170 expression system

主题词动物(Animals);抗菌药(Anti-Bacterial Agents);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);基因表达(Gene Expression);葡糖氨基聚糖类(Glycosaminoglycans);人类(Humans);乳乳球菌(Lactococcus lactis);乳铁蛋白(Lactoferrin);肽类(Peptides)

DOI 10.1007/s12602-018-9496-6

PMID 30552573

发布时间 2020-04-08

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Probiotics and antimicrobial proteins

Probiotics and antimicrobial proteins

2019年11卷3期

1034-1041页

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