Pharmacokinetics of Prolonged-Release Once-Daily Formulations of Tacrolimus in De Novo Kidney Transplant Recipients: A Randomized, Parallel-Group, Open-Label, Multicenter Study.

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作者： Nassim,Kamar ^[1] ; Elisabeth,Cassuto ^[2] ; Giovanni,Piotti ^[3] ; Mirco,Govoni ^[4] ; Giorgia,Ciurlia ^[5] ; Silvia,Geraci ^[4] ; Gianluigi,Poli ^[4] ; Gabriele,Nicolini ^[4] ; Christophe,Mariat ^[4] ; Marie,Essig ^[6] ; Paolo,Malvezzi ^[7] ; Yannick,Le Meur ^[8] ; Valerie,Garrigue ^[9] ; Arnaud,Del Bello ^[10] ; Lionel,Rostaing ^[1]

作者单位： Departments of Nephrology and Organ Transplantation, CHU Rangueil, INSERM U1043, IFR-BMT, Université Paul Sabatier, Toulouse, France. ^[1] Unité de Transplantation Rénale, Hôpital Pasteur 2, CHU Nice, Nice, France. ^[2] Kidney and Pancreas Transplantation Unit, University Hospital of Parma, 43121, Parma, Italy. ^[3] Global Clinical Development, Department of Clinical Pharmacology, Chiesi Farmaceutici, Parma, Italy. ^[4] Global Clinical Development, Department of Clinical Pharmacology, Chiesi Farmaceutici, Parma, Italy. M.Govoni@chiesi.com. ^[5] CHU Saint-Etienne, Hôpital Nord Avenue Albert Raimond, Saint Priest en Jarez, France. ^[6] Nephrology Unit, CHU Limoges, 2 Avenue Martin Luther King, Limoges, France. ^[7] Service de Néphrologie, Dialyse, Aphérèses et Transplantation, CHU Grenoble Alpes, Grenoble, France. ^[8] Service de Nephrologie-Transplantation Rénale et Hémodialyse, CHRU Brest, Hôpital de la Cavale Blanche, Brest, France. ^[9] Service de Néphrologie-Transplantation-Dialyse péritonéale CHU Lapeyronie, Montpellier, France. ^[10]

关键词 Advagraf De novo kidney transplantation Envarsus LCPT PR Tac Pharmacokinetics Tacrolimus