Design and synthesis of biaryloxazolidinone derivatives containing a rhodanine or thiohydantoin moiety as novel antibacterial agents against Gram-positive bacteria.
第一作者:
Yachuang,Wu
第一单位:
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
作者:
医学主题词
抗菌药(Anti-Bacterial Agents);细胞存活(Cell Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);革兰氏阳性菌(Gram-Positive Bacteria);Hep G2细胞(Hep G2 Cells);人类(Humans);微生物敏感性试验(Microbial Sensitivity Tests);分子结构(Molecular Structure);单胺氧化酶(Monoamine Oxidase);单胺氧化酶抑制剂(Monoamine Oxidase Inhibitors);绕丹宁(Rhodanine);构效关系(Structure-Activity Relationship);硫海因类(Thiohydantoins)
DOI
10.1016/j.bmcl.2018.12.012
PMID
30553735
发布时间
2019-12-17
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