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首页> Frontiers in immunology> Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization.

Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization.

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作者： Aneesh,Thakur ^[1] ; Cristina,Rodríguez-Rodríguez ^[2] ; Katayoun,Saatchi ^[3] ; Fabrice,Rose ^[2] ; Tullio,Esposito ^[1] ; Zeynab,Nosrati ^[2] ; Peter,Andersen ^[2] ; Dennis,Christensen ^[4] ; Urs O,Häfeli ^[4] ; Camilla,Foged ^[2]

作者单位： Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ^[1] Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada. ^[2] Department of Physics and Astronomy, The University of British Columbia, Vancouver, BC, Canada. ^[3] Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark. ^[4]

关键词 H56/CAF01 vaccine SPECT/CT imaging T cells drug delivery dual-isotope 111In/67Ga mucosal immunity nanomedicine pulmonary immunization

主题词动物(Animals);抗体, 细菌(Antibodies, Bacterial);女(雌)性(Female);免疫, 黏膜(Immunity, Mucosal);免疫接种, 加强(Immunization, Secondary);免疫球蛋白A(Immunoglobulin A);肺(Lung);小鼠(Mice);结核分枝杆菌(Mycobacterium tuberculosis);T淋巴细胞(T-Lymphocytes);结核菌苗(Tuberculosis Vaccines);疫苗, 亚单位(Vaccines, Subunit)

DOI 10.3389/fimmu.2018.02825

PMID 30555488

发布时间 2020-03-09

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Frontiers in immunology

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