Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.

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第一作者： Shoma,Tamori

第一单位： Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.

作者： Shoma,Tamori ^[1] ; Yuka,Nozaki ^[2] ; Hitomi,Motomura ^[1] ; Hiromi,Nakane ^[2] ; Reika,Katayama ^[1] ; Chotaro,Onaga ^[2] ; Eriko,Kikuchi ^[1] ; Nami,Shimada ^[1] ; Yuhei,Suzuki ^[1] ; Mei,Noike ^[1] ; Yasushi,Hara ^[3] ; Keiko,Sato ^[1] ; Tsugumichi,Sato ^[1] ; Kouji,Yamamoto ^[4] ; Takehisa,Hanawa ^[5] ; Misa,Imai ^[2] ; Ryo,Abe ^[3] ; Atsushi,Yoshimori ^[2] ; Ryoko,Takasawa ^[6] ; Sei-Ichi,Tanuma ^[2] ; Kazunori,Akimoto ^[3]

作者单位： Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan. ^[1] Translational Research Center, Research Institute for Science and Technology, Tokyo University of Science, Chiba, Japan. ^[2] Department of Pharmacy, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan. ^[3] Research Institute for Biochemical Sciences, Tokyo University of Science, Chiba, Japan. ^[4] Department of Information Sciences, Faculty of Science and Technology, Tokyo University of Science, Chiba, Japan. ^[5] Department of Biostatistics, Yokohama City University, School of Medicine, Yokohama, Japan. ^[6] Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan. ^[7] Leading Center for the Development and Research of Cancer Medicine, Juntendo University School of Medicine, Tokyo, Japan. ^[8] Strategic Innovation and Research Center, Teikyo University, Tokyo, Japan. ^[9] Institute for Theoretical Medicine, Inc., Kanagawa, Japan. ^[10] Laboratory of Genomic Medicinal Science, Research Institute for Science and Technology, Tokyo University of Science, Chiba, Japan. ^[11]

关键词 breast cancer cancer stem cell glyoxalase 1 target therapy the Warburg effect

DOI 10.18632/oncotarget.26369

PMID 30559934

发布时间 2023-10-04

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