首页> Nature communications> HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.

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第一作者： Jie,Zheng

第一单位： Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. jzheng@scripps.edu.

作者： Jie,Zheng ^[1] ; Chen,Wang ^[2] ; Mi Ra,Chang ^[3] ; Swapnil C,Devarkar ^[4] ; Brandon,Schweibenz ^[4] ; Gogce C,Crynen ^[5] ; Ruben D,Garcia-Ordonez ^[3] ; Bruce D,Pascal ^[6] ; Scott J,Novick ^[3] ; Smita S,Patel ^[4] ; Joseph,Marcotrigiano ^[7] ; Patrick R,Griffin ^[8]

作者单位： Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. jzheng@scripps.edu. ^[1] Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. ^[2] Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. ^[3] Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA. ^[4] The Center for Computational Biology, The Scripps Research Institute, Jupiter, FL, 33458, USA. ^[5] Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.;Omics Informatics LLC, Honolulu, HI 96813, USA. ^[6] Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. joseph.marcotrigiano@nih.gov. ^[7] Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. pgriffin@scripps.edu. ^[8]