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Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins.

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第一作者： Oeystein Roed,Brekk

第一单位： Center of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, Athens, Greece; University of Crete, School of Medicine, Heraklion, Crete, Greece. Electronic address: obrekk@mclean.harvard.edu.

作者： Oeystein Roed,Brekk ^[1] ; Manousos,Makridakis ^[2] ; Panagiota,Mavroeidi ^[3] ; Antonia,Vlahou ^[2] ; Maria,Xilouri ^[3] ; Leonidas,Stefanis ^[4]

作者单位： Center of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, Athens, Greece; University of Crete, School of Medicine, Heraklion, Crete, Greece. Electronic address: obrekk@mclean.harvard.edu. ^[1] Biotechnology Division, Biomedical Research Foundation, Academy of Athens, Athens, Greece. ^[2] Center of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, Athens, Greece. ^[3] Center of Clinical Research, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, Athens, Greece; Second Department of Neurology, National and Kapodistrian University of Athens Medical School, Athens, Greece. Electronic address: lstefanis@bioacademy.gr. ^[4]

关键词 Chaperone-mediated autophagy (CMA)DPYSL2/CRMP-2 LAMP2A PARK7/DJ-1 Parkinson's Disease (PD)Proteomics Schizophrenia