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首页> Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie> Folate receptor targeted delivery of paclitaxel to breast cancer cells via folic acid conjugated graphene oxide grafted methyl acrylate nanocarrier.

Folate receptor targeted delivery of paclitaxel to breast cancer cells via folic acid conjugated graphene oxide grafted methyl acrylate nanocarrier.

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作者： Kandasamy,Vinothini ^[1] ; Naresh Kumar,Rajendran ^[2] ; Andy,Ramu ^[1] ; Nandhakumar,Elumalai ^[3] ; Mariappan,Rajan ^[4]

作者单位： Biomaterials in Medicinal Chemistry Laboratory, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India. ^[1] Department of Inorganic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India. ^[2] Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein 2028, Johannesburg, South Africa. ^[3] Biomaterials in Medicinal Chemistry Laboratory, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India. Electronic address: rajanm153@gmail.com. ^[4]

关键词 Breast cancer rats Caspases Cytotoxicity Drug delivery Folic acid Graphene oxide Nanocarrier Paclitaxel

主题词丙烯酸盐类(Acrylates);动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物载体(Drug Carriers);药物释放系统(Drug Delivery Systems);女(雌)性(Female);叶酸盐受体, GPI锚连(Folate Receptors, GPI-Anchored);叶酸(Folic Acid);石墨(Graphite);纳米粒子(Nanoparticles);紫杉酚(Paclitaxel);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley)

DOI 10.1016/j.biopha.2018.12.008

PMID 30572195

发布时间 2019-04-18

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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