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High-dimensional single-cell proteomics analysis identifies immune checkpoint signatures and therapeutic targets in ulcerative colitis.

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第一作者： Sebastian,Fuchs

第一单位： Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases (I3) Discovery and Translational Area, Roche Innovation Center Basel, Basel, Switzerland.

作者： Sebastian,Fuchs ^[1] ; Nadia,Sawas ^[1] ; Nicolas,Staedler ^[2] ; David A,Schubert ^[1] ; Annalisa,D'Andrea ^[1] ; Robert,Zeiser ^[3] ; Luca,Piali ^[1] ; Petr,Hruz ^[4] ; Andreas P,Frei ^[1]

作者单位： Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases (I3) Discovery and Translational Area, Roche Innovation Center Basel, Basel, Switzerland. ^[1] Roche Pharma Research and Early Development, Pharmaceutical Sciences, BiOmics, Roche Innovation Center Basel, Basel, Switzerland. ^[2] Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany. ^[3] Department of Gastroenterology, University Hospital, Basel, Switzerland. ^[4]

关键词 CyTOF immune checkpoints inflammation single-cell proteomics ulcerative colitis