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Mitochondrial damage-associated molecular patterns released by lung transplants are associated with primary graft dysfunction.

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第一作者： Davide,Scozzi

第一单位： Department of Surgery, Washington University School, St. Louis, Missouri.;Department of Clinical & Molecular Medicine, Sapienza University of Rome, Rome, Italy.

作者： Davide,Scozzi ^[1] ; Mohsen,Ibrahim ^[2] ; Fuyi,Liao ^[3] ; Xue,Lin ^[3] ; Hsi-Min,Hsiao ^[3] ; Ramsey,Hachem ^[4] ; Laneshia K,Tague ^[4] ; Alberto,Ricci ^[5] ; Hrishikesh S,Kulkarni ^[4] ; Howard J,Huang ^[6] ; Seiichiro,Sugimoto ^[7] ; Alexander S,Krupnick ^[8] ; Daniel,Kreisel ^[9] ; Andrew E,Gelman ^[10]

作者单位： Department of Surgery, Washington University School, St. Louis, Missouri.;Department of Clinical & Molecular Medicine, Sapienza University of Rome, Rome, Italy. ^[1] Department of Surgery, Washington University School, St. Louis, Missouri.;Department Medical-Surgical Science & Translational Medicine, Sapienza University of Rome, Rome, Italy. ^[2] Department of Surgery, Washington University School, St. Louis, Missouri. ^[3] Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. ^[4] Department of Clinical & Molecular Medicine, Sapienza University of Rome, Rome, Italy. ^[5] Houston Methodist J. C. Walter Jr. Transplant Center, Houston, Texas. ^[6] Department of General Thoracic Surgery, Okayama University Hospital, Okayama, Japan. ^[7] Department of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia. ^[8] Department of Surgery, Washington University School, St. Louis, Missouri.;Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri. ^[9] Department of Surgery, Washington University School, St. Louis, Missouri.;Department Medical-Surgical Science & Translational Medicine, Sapienza University of Rome, Rome, Italy.;Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri. ^[10]

关键词 animal models basic (laboratory) research/science cellular biology clinical research/practice immunobiology innate immunity ischemia-reperfusion injury (IRI)lung (allograft) function/dysfunction lung transplantation/pulmonology mouse

DOI 10.1111/ajt.15232

PMID 30582269

发布时间 2023-03-22

基金项目

R01 AI145108/AI/NIAID NIH HHS/United States R01 HL121218/HL/NHLBI NIH HHS/United States R01 HL113436/HL/NHLBI NIH HHS/United States P01 AI116501/AI/NIAID NIH HHS/United States R01 HL094601/HL/NHLBI NIH HHS/United States

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