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首页> Journal of molecular and cellular cardiology> Decreased α-tubulin acetylation induced by an acidic environment impairs autophagosome formation and leads to rat cardiomyocyte injury.

Decreased α-tubulin acetylation induced by an acidic environment impairs autophagosome formation and leads to rat cardiomyocyte injury.

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作者： Lei,Yang ^[1] ; Liping,Zhao ^[2] ; Lin,Cui ^[1] ; Yao,Huang ^[1] ; Jingying,Ye ^[1] ; Qiong,Zhang ^[1] ; Xupin,Jiang ^[1] ; Dongxia,Zhang ^[3] ; Yuesheng,Huang ^[4]

作者单位： Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, Third Military Medical University, Chongqing, China. ^[1] Department of Plastic Surgery, Nanjing Medical University Friendship Plastic Surgery Hospital, Nanjing 210029, Jiangsu Province, China. ^[2] Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, Third Military Medical University, Chongqing, China. Electronic address: dxzhangswh@163.com. ^[3] Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, Third Military Medical University, Chongqing, China. Electronic address: yshuangtmmu@163.com. ^[4]

关键词 Autophagy Cardiomyocyte HDAC6 pH α-Tubulin acetylation

主题词乙酰化作用(Acetylation);动物(Animals);自噬(Autophagy);细胞存活(Cell Survival);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);氢离子浓度(Hydrogen-Ion Concentration);肌细胞, 心脏(Myocytes, Cardiac);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);微管蛋白(Tubulin)

DOI 10.1016/j.yjmcc.2018.12.011

PMID 30582931

发布时间 2020-01-08

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Journal of molecular and cellular cardiology

143-153页

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