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首页> Metabolic engineering> Engineering Pseudomonas entomophila for synthesis of copolymers with defined fractions of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoates.

Engineering Pseudomonas entomophila for synthesis of copolymers with defined fractions of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoates.

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作者： Mengyi,Li ^[1] ; Xiangbin,Chen ^[2] ; Xuemei,Che ^[3] ; Haoqian,Zhang ^[4] ; Lin-Ping,Wu ^[5] ; Hetong,Du ^[2] ; Guo-Qiang,Chen ^[6]

作者单位： Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China. ^[1] School of Life Sciences, Tsinghua University, Beijing 100084, China. ^[2] Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China; Center for Nano- and Micro-Mechanics, Tsinghua University, Beijing 100084, China. ^[3] Bluepha Co., Ltd., Beijing 102206, China. ^[4] Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China. ^[5] Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China; School of Life Sciences, Tsinghua University, Beijing 100084, China; Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China; Center for Nano- and Micro-Mechanics, Tsinghua University, Beijing 100084, China. Electronic address: chengq@mail.tsinghua.edu.cn. ^[6]

关键词 Metabolic engineering PHB Polyhydroxyalkanoates Pseudomonas entomophila Synthetic biology β-Oxidation

主题词 3-羟基丁酸(3-Hydroxybutyric Acid);酰基转移酶类(Acyltransferases);脂肪酸类(Fatty Acids);脂肪酸类, 挥发性(Fatty Acids, Volatile);基因敲除技术(Gene Knockout Techniques);分子量(Molecular Weight);氧化还原(Oxidation-Reduction);质粒(Plasmids);聚羟基脂肪酸酯类(Polyhydroxyalkanoates);聚合物(Polymers);假单胞菌属(Pseudomonas)

DOI 10.1016/j.ymben.2018.12.007

PMID 30582985

发布时间 2020-09-30

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