Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer.

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作者： Guido,Keijzers ^[1] ; Daniela,Bakula ^[2] ; Michael Angelo,Petr ^[3] ; Nils Gedsig Kirkelund,Madsen ^[4] ; Amanuel,Teklu ^[5] ; Garik,Mkrtchyan ^[6] ; Brenna,Osborne ^[7] ; Morten,Scheibye-Knudsen ^[8]

作者单位： Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. guido@sund.ku.dk. ^[1] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. bakula@sund.ku.dk. ^[2] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. mapetr@sund.ku.dk. ^[3] Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA. mapetr@sund.ku.dk. ^[4] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. ngkm@sund.ku.dk. ^[5] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. amanuel@sund.ku.dk. ^[6] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. garik@sund.ku.dk. ^[7] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. brenna@sund.ku.dk. ^[8] Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark. mscheibye@sund.ku.dk. ^[9]

关键词 DNA repair EXO1 MMR NER TLS double strand break repair exonuclease 1 mismatch repair nucleotide excision repair strand displacements translesion DNA synthesis