Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression.

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作者： Tsuyoshi,Shimo ^[1] ; Eiki,Koyama ^[2] ; Tatsuo,Okui ^[3] ; Masanori,Masui ^[3] ; Yuki,Kunisada ^[3] ; Soichiro,Ibaragi ^[3] ; Norie,Yoshioka ^[3] ; Naito,Kurio ^[4] ; Shoko,Yoshida ^[3] ; Akira,Sasaki ^[3] ; Masahiro,Iwamoto ^[5]

作者单位： Division of Reconstructive Surgery for Oral and Maxillofacial Region, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan shimotsu@hoku-iryo-u.ac.jp. ^[1] Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A. ^[2] Department of Oral and Maxillofacial Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan. ^[3] Department of Oral Surgery, Tokushima University Graduate School, Tokushima, Japan. ^[4] Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, U.S.A. ^[5]

关键词 Retinoid signaling chondrocyte maturation connective tissue growth factor matrix metalloproteinase mitogen-activated protein kinase

主题词动物(Animals);软骨(Cartilage);细胞分化(Cell Differentiation);软骨细胞(Chondrocytes);胶原Ⅹ型(Collagen Type X);结缔组织生长因子(Connective Tissue Growth Factor);基因表达调控, 发育期(Gene Expression Regulation, Developmental);人类(Humans);原位杂交(In Situ Hybridization);基质金属蛋白酶13(Matrix Metalloproteinase 13);小鼠(Mice);磷酰化(Phosphorylation);RNA, 信使(RNA, Messenger);受体, 维甲酸(Receptors, Retinoic Acid);信号传导(Signal Transduction);胫骨(Tibia);维甲酸(Tretinoin);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)

DOI 10.21873/invivo.11443

PMID 30587607

发布时间 2023-12-13

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Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression.

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Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression.

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