Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier.

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作者： Monica,Corada ^[1] ; Fabrizio,Orsenigo ^[1] ; Ganesh Parameshwar,Bhat ^[2] ; Lei Liu,Conze ^[3] ; Ferruccio,Breviario ^[1] ; Sara Isabel,Cunha ^[3] ; Lena,Claesson-Welsh ^[3] ; Galina V,Beznoussenko ^[1] ; Alexander A,Mironov ^[1] ; Marco,Bacigaluppi ^[4] ; Gianvito,Martino ^[4] ; Mara E,Pitulescu ^[5] ; Ralf H,Adams ^[5] ; Peetra,Magnusson ^[3] ; Elisabetta,Dejana ^[1]

作者单位： From the FIRC Institute of Molecular Oncology Foundation (IFOM), Milan, Italy (M.C., F.O., F.B., G.V.B., A.A.M., E.D.). ^[1] Molecular Neurobiology Laboratory, Division of Neuroscience (G.P.B.), San Raffaele Hospital, Milan, Italy. ^[2] Rudbeck Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden (L.L.C., S.I.C., L.C.-W., P.M., E.D.). ^[3] Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology (M.B., G.M.), San Raffaele Hospital, Milan, Italy. ^[4] Department of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine and Faculty of Medicine, University of Münster, Germany (M.E.P., R.H.A.). ^[5] Department of Oncology and Hemato-Oncology, University of Milan, Italy (E.D.). ^[6]

关键词 Wnt/β-catenin blood-brain barrier endothelial cells permeability stroke

主题词动物(Animals);血脑屏障(Blood-Brain Barrier);毛细血管通透性(Capillary Permeability);HMGB蛋白质类(HMGB Proteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);SOXF转录因子类(SOXF Transcription Factors)

DOI 10.1161/CIRCRESAHA.118.313316

PMID 30591003

发布时间 2020-03-09

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