Endolysosomal Ca<sup>2+</sup> Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind!

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作者： Pawan,Faris ^[1] ; Mudhir,Shekha ^[2] ; Daniela,Montagna ^[3] ; Germano,Guerra ^[4] ; Francesco,Moccia ^[5]

作者单位： Laboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy. pawan.faris@yahoo.com. ^[1] Research Centre, Salahaddin University-Erbil, Erbil 44001, Kurdistan-Region of Iraq, Iraq. pawan.faris@yahoo.com. ^[2] Research Centre, Salahaddin University-Erbil, Erbil 44001, Kurdistan-Region of Iraq, Iraq. mudhir.shekha@su.edu.krd. ^[3] Department of Pathological Analysis, College of Science, Knowledge University, Erbil 074016, Kurdistan-Region of Iraq, Iraq. mudhir.shekha@su.edu.krd. ^[4] Laboratory of Immunology Transplantation, Foundation IRCCS Policlinico San Matteo, 27100 Pavia, Italy. d.montagna@smatteo.pv.it. ^[5] Department of Sciences Clinic-Surgical, Diagnostic and Pediatric, University of Pavia, 27100 Pavia, Italy. d.montagna@smatteo.pv.it. ^[6] Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, 86100 Campobasso, Italy. germano.guerra@unimol.it. ^[7] Laboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy. francesco.moccia@unipv.it. ^[8]

关键词 NAADP TPCs TRPML1 angiogenesis cancer endolysosomal Ca2+ signaling metastasis proliferation

DOI 10.3390/cancers11010027

PMID 30591696

发布时间 2020-10-01

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