Triptonide inhibits lung cancer cell tumorigenicity by selectively attenuating the Shh-Gli1 signaling pathway.

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作者： Mengli,Zhang ^[1] ; Shijie,Tan ^[1] ; Di,Yu ^[2] ; Zhe,Zhao ^[1] ; Bin,Zhang ^[1] ; Pan,Zhang ^[1] ; Chunping,Lv ^[1] ; Quansheng,Zhou ^[3] ; Zhifei,Cao ^[4]

作者单位： Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, 2011 Collaborative Innovation Center of Hematology, Soochow University; Suzhou, Jiangsu 215123, PR China. ^[1] Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu 214122, PR China. ^[2] Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, 2011 Collaborative Innovation Center of Hematology, Soochow University; Suzhou, Jiangsu 215123, PR China. Electronic address: zhouqs@suda.edu.cn. ^[3] Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, 2011 Collaborative Innovation Center of Hematology, Soochow University; Suzhou, Jiangsu 215123, PR China. Electronic address: zhfcao@suda.edu.cn. ^[4]

关键词 Cancer therapy Gli1 Lung cancer Shh Signaling pathway Triptonide