Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death.

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作者： Xinfang,An ^[1] ; Zixing,Fu ^[2] ; Chendi,Mai ^[3] ; Weiming,Wang ^[4] ; Linyu,Wei ^[5] ; Dongliang,Li ^[6] ; Chaokun,Li ^[7] ; Lin-Hua,Jiang ^[8]

作者单位： Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. anxinfang2018@126.com. ^[1] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. fuzixing1991@126.com. ^[2] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. mcdhsm@163.com. ^[3] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. wangweiming2015@126.com. ^[4] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. wly98124@126.com. ^[5] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. xyldl8@126.com. ^[6] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. lichaokun@hotmail.com. ^[7] Sino-UK Joint Laboratory for Brain Function and Injury and Department of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang 453003, China. l.h.jiang@leeds.ac.uk. ^[8] School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 JT, UK. l.h.jiang@leeds.ac.uk. ^[9]

关键词 ROS TRPM2 channel human neuroblastoma SH-SY5Y cells neuronal cell death

主题词阿尔茨海默病(Alzheimer Disease);硼化合物(Boron Compounds);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);人类(Humans);过氧化氢(Hydrogen Peroxide);模型, 生物学(Models, Biological);神经母细胞瘤(Neuroblastoma);神经变性疾病(Neurodegenerative Diseases);帕金森病, 继发性(Parkinson Disease, Secondary);菲类(Phenanthrenes);活性氧(Reactive Oxygen Species);TRPM阳离子通道(TRPM Cation Channels)

DOI 10.3390/cells8010028

PMID 30625984

发布时间 2020-03-09

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Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death.

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Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death.

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