HIV-Related Arterial Stiffness in Malawian Adults Is Associated With the Proportion of PD-1-Expressing CD8+ T Cells and Reverses With Antiretroviral Therapy.

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作者： Christine,Kelly ^[1] ; Henry C,Mwandumba ^[2] ; Robert S,Heyderman ^[3] ; Kondwani,Jambo ^[4] ; Raphael,Kamng'ona ^[2] ; Mishek,Chammudzi ^[5] ; Irene,Sheha ^[6] ; Ingrid,Peterson ^[2] ; Alicja,Rapala ^[4] ; Jane,Mallewa ^[2] ; A Sarah,Walker ^[2] ; Nigel,Klein ^[2] ; Saye,Khoo ^[2]

作者单位： Insitute of Translational Medicine, University of Liverpool. ^[1] Malawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine. ^[2] HIV Molecular Research Group, University College Dublin, Ireland. ^[3] Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool. ^[4] Department of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi. ^[5] Division of Infection and Immunity. ^[6] Institute for Cardiovascular Sciences. ^[7] MRC Clinical Trials Unit. ^[8] Institute of Child Health, University College London, London, United Kingdom. ^[9]

关键词 HIV PD-1 T-cell exhaustion arterial stiffness cardiovascular disease endothelial damage sub-Saharan Africa

主题词成年人(Adult);抗逆转录病毒药(Anti-Retroviral Agents);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);HIV感染(HIV Infections);人类(Humans);马拉维(Malawi);男(雄)性(Male)

DOI 10.1093/infdis/jiz015

PMID 30629187

发布时间 2024-03-06

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准确一般字义偏差语意偏离译文作用小提交