Acidosis enhances the self-renewal and mitochondrial respiration of stem cell-like glioma cells through CYP24A1-mediated reduction of vitamin D.

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作者： Peishan,Hu ^[1] ; Shanshan,Li ^[1] ; Ningyu,Tian ^[1] ; Fan,Wu ^[2] ; Yan,Hu ^[1] ; Dengke,Li ^[1] ; Yingjiao,Qi ^[1] ; Zhizhong,Wei ^[1] ; Qunfang,Wei ^[1] ; Yanchao,Li ^[1] ; Bin,Yin ^[1] ; Tao,Jiang ^[2] ; Jiangang,Yuan ^[3] ; Boqin,Qiang ^[1] ; Wei,Han ^[1] ; Xiaozhong,Peng ^[4]

作者单位： State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. ^[1] Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. ^[2] Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. ^[3] State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. hanwei2012@ibms.pumc.edu.cn. ^[4] State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. pengxiaozhong@pumc.edu.cn. ^[5] Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming, China. pengxiaozhong@pumc.edu.cn. ^[6]