Sumoylation of Flotillin-1 promotes EMT in metastatic prostate cancer by suppressing Snail degradation.
第一作者:
Donghwan,Jang
第一单位:
Division of Life Science, Graduate School of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828, South Korea.
作者:
医学主题词
细胞系, 肿瘤(Cell Line, Tumor);细胞核(Cell Nucleus);上皮-间质转化(Epithelial-Mesenchymal Transition);人类(Humans);男(雄)性(Male);膜蛋白质类(Membrane Proteins);前列腺肿瘤(Prostatic Neoplasms);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质转运(Protein Transport);信号传导(Signal Transduction);SUMO化(Sumoylation);转录因子(Transcription Factors);泛素缀合酶类(Ubiquitin-Conjugating Enzymes);增量调节(Up-Regulation)
DOI
10.1038/s41388-018-0641-1
PMID
30631151
发布时间
2025-01-03
- 浏览52
Oncogene
3248-3260页
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