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Heterozygous <i>Tbk1</i> loss has opposing effects in early and late stages of ALS in mice.

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第一作者： David,Brenner

第一单位： Department of Neurology, University of Ulm, Ulm, Germany.

作者： David,Brenner ^[1] ; Kirsten,Sieverding ^[1] ; Clara,Bruno ^[1] ; Patrick,Lüningschrör ^[2] ; Eva,Buck ^[1] ; Simon,Mungwa ^[2] ; Lena,Fischer ^[1] ; Sarah J,Brockmann ^[1] ; Johannes,Ulmer ^[1] ; Corinna,Bliederhäuser ^[1] ; Clémentine E,Philibert ^[3] ; Takashi,Satoh ^[4] ; Shizuo,Akira ^[4] ; Séverine,Boillée ^[3] ; Benjamin,Mayer ^[5] ; Michael,Sendtner ^[2] ; Albert C,Ludolph ^[1] ; Karin M,Danzer ^[1] ; Christian S,Lobsiger ^[3] ; Axel,Freischmidt ^[1] ; Jochen H,Weishaupt ^[6]

作者单位： Department of Neurology, University of Ulm, Ulm, Germany. ^[1] Institute of Clinical Neurobiology, University Hospital of Wuerzburg, Wuerzburg, Germany. ^[2] Institut du Cerveau et de la Moelle Épinière, Institut National de la Santé et de la Recherche Médicale Unité 1127, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7225, Sorbonne Université, Paris, France. ^[3] Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan. ^[4] Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany. ^[5] Department of Neurology, University of Ulm, Ulm, Germany jochen.weishaupt@uni-ulm.de. ^[6]