The Emergence and Functional Fitness of Memory CD4<sup>+</sup> T Cells Require the Transcription Factor Thpok.

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第一作者： Thomas,Ciucci

第一单位： Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

作者： Thomas,Ciucci ^[1] ; Melanie S,Vacchio ^[1] ; Yayi,Gao ^[1] ; Francesco,Tomassoni Ardori ^[2] ; Julian,Candia ^[3] ; Monika,Mehta ^[4] ; Yongmei,Zhao ^[4] ; Bao,Tran ^[4] ; Marion,Pepper ^[5] ; Lino,Tessarollo ^[2] ; Dorian B,McGavern ^[6] ; Rémy,Bosselut ^[7]

作者单位： Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. ^[1] Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA. ^[2] Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation, National Institutes of Health, Bethesda, MD, USA. ^[3] Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA. ^[4] Department of Immunology, University of Washington School of Medicine, Seattle, WA, USA. ^[5] Viral Immunology and Intravital Imaging Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. ^[6] Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: remy.bosselut@nih.gov. ^[7]

关键词 CD4 T?cell LCMV T cell dysfunction T cell memory Thpok immune response single-cell RNA-seq transcription factor