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Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins.

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第一作者： April L,Darling

第一单位： Department of Molecular Medicine, College of Medicine, Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33612, USA. Electronic address: aldarlin@mail.usf.edu.

作者： April L,Darling ^[1] ; Leonid,Breydo ^[2] ; Emma G,Rivas ^[2] ; Niad T,Gebru ^[2] ; Dali,Zheng ^[2] ; Jeremy D,Baker ^[2] ; Laura J,Blair ^[2] ; Chad A,Dickey ^[2] ; John,Koren ^[3] ; Vladimir N,Uversky ^[4]

作者单位： Department of Molecular Medicine, College of Medicine, Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33612, USA. Electronic address: aldarlin@mail.usf.edu. ^[1] Department of Molecular Medicine, College of Medicine, Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33612, USA. ^[2] Department of Molecular Medicine, College of Medicine, Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33612, USA. Electronic address: jkoren@nd.edu. ^[3] Department of Molecular Medicine, College of Medicine, Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33612, USA; Institute for Biological Instrumentation of the Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russia. Electronic address: vuversky@health.usf.edu. ^[4]

关键词 ALS C9orf72 Dipeptide repeat protein FTD Intrinsically disordered proteins Poly(GA)Poly(PR)

医学主题词肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);细胞系(Cell Line);二肽类(Dipeptides);额颞叶痴呆(Frontotemporal Dementia);人类(Humans);重复序列, 氨基酸(Repetitive Sequences, Amino Acid)

DOI 10.1016/j.ijbiomac.2019.01.035

PMID 30639592

发布时间 2019-06-20

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