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Discovery of a ZIP7 inhibitor from a Notch pathway screen.

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第一作者： Erin,Nolin

第一单位： Novartis Institutes for Biomedical Research, Cambridge, MA, USA.

作者： Erin,Nolin ^[1] ; Sara,Gans ^[1] ; Luis,Llamas ^[1] ; Somnath,Bandyopadhyay ^[1] ; Scott M,Brittain ^[1] ; Paula,Bernasconi-Elias ^[1] ; Kyle P,Carter ^[2] ; Joseph J,Loureiro ^[1] ; Jason R,Thomas ^[1] ; Markus,Schirle ^[1] ; Yi,Yang ^[1] ; Ning,Guo ^[1] ; Guglielmo,Roma ^[3] ; Sven,Schuierer ^[3] ; Martin,Beibel ^[3] ; Alicia,Lindeman ^[1] ; Frederic,Sigoillot ^[1] ; Amy,Chen ^[1] ; Kevin X,Xie ^[1] ; Samuel,Ho ^[1] ; John,Reece-Hoyes ^[1] ; Wilhelm A,Weihofen ^[1] ; Kayla,Tyskiewicz ^[1] ; Dominic,Hoepfner ^[3] ; Richard I,McDonald ^[1] ; Nicolette,Guthrie ^[1] ; Abhishek,Dogra ^[1] ; Haibing,Guo ^[4] ; Jian,Shao ^[1] ; Jian,Ding ^[1] ; Stephen M,Canham ^[1] ; Geoff,Boynton ^[1] ; Elizabeth L,George ^[1] ; Zhao B,Kang ^[1] ; Christophe,Antczak ^[1] ; Jeffery A,Porter ^[1] ; Owen,Wallace ^[1] ; John A,Tallarico ^[1] ; Amy E,Palmer ^[2] ; Jeremy L,Jenkins ^[1] ; Rishi K,Jain ^[1] ; Simon M,Bushell ^[5] ; Christy J,Fryer ^[6]

作者单位： Novartis Institutes for Biomedical Research, Cambridge, MA, USA. ^[1] Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, CO, USA. ^[2] Novartis Institutes for Biomedical Research, Basel, Switzerland. ^[3] Novartis Institutes for Biomedical Research, Shanghai, China. ^[4] Novartis Institutes for Biomedical Research, Cambridge, MA, USA. simon.bushell@novartis.com. ^[5] Novartis Institutes for Biomedical Research, Cambridge, MA, USA. christy.fryer@novartis.com. ^[6]