换一批Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity.
第一作者：
Ming-Ming,Hu
第一单位：
Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. mmhu@whu.edu.cn.;Medical Research Institute, School of Medicine, Wuhan University, Wuhan, 430071, China. mmhu@whu.edu.cn.;State Key Laboratory of Virology, Wuhan University, Wuhan, 430072, China. mmhu@whu.edu.cn.
作者：
医学主题词
动物(Animals);胆汁酸类和盐类(Bile Acids and Salts);载体蛋白质类(Carrier Proteins);细胞系(Cell Line);HEK293细胞(HEK293 Cells);单纯疱疹(Herpes Simplex);疱疹病毒1型, 人(Herpesvirus 1, Human);人类(Humans);免疫, 先天(Immunity, Innate);膜糖蛋白类(Membrane Glycoproteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);NF-κB(NF-kappa B);磷酰化(Phosphorylation);原癌基因蛋白质类pp60(c-src)(Proto-Oncogene Proteins pp60(c-src));受体, G-蛋白偶联(Receptors, G-Protein-Coupled)
DOI
10.1038/s41422-018-0136-1
PMID
30651583
发布时间
2022-04-16
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Cell research
193-205页
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