Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.-论文-万方医学网

作者： Wenxin,Song ^[1] ; Qi,Luo ^[1] ; Yuping,Zhang ^[2] ; Linkang,Zhou ^[3] ; Ye,Liu ^[1] ; Zhilong,Ma ^[4] ; Jianan,Guo ^[1] ; Yuedong,Huang ^[1] ; Lili,Cheng ^[1] ; Ziyi,Meng ^[1] ; Zicheng,Li ^[1] ; Bin,Zhang ^[1] ; Siqi,Li ^[4] ; Sook Wah,Yee ^[5] ; Hao,Fan ^[1] ; Peng,Li ^[2] ; Kathleen M,Giacomini ^[3] ; Ligong,Chen ^[6]

作者单位： School of Pharmaceutical Sciences, Tsinghua University, Beijing, China. ^[1] Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, California. ^[2] Institute for Human Genetics, University of California, San Francisco, California. ^[3] State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. ^[4] Institute of Immunology, School of Medicine, Tsinghua University, Beijing, China. ^[5] Bioinformatics Institute, Agency for Science, Technology and Research, Singapore; Department of Biological Sciences, National University of Singapore, Singapore; Centre for Computational Biology, DUKE-NUS Medical School, Singapore. ^[6] Collaborative Innovation Center for Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China. ^[7]

主题词脂细胞(Adipocytes);脂肪组织(Adipose Tissue);脂肪组织, 白色(Adipose Tissue, White);动物(Animals);儿茶酚胺类(Catecholamines);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);能量代谢(Energy Metabolism);HEK293细胞(HEK293 Cells);人类(Humans);巨噬细胞(Macrophages);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);去甲肾上腺素(Norepinephrine);去甲肾上腺素质膜转运蛋白质类(Norepinephrine Plasma Membrane Transport Proteins);肥胖症(Obesity);八聚体转录因子3(Octamer Transcription Factor-3);有机阳离子转运蛋白质类(Organic Cation Transport Proteins);信号传导(Signal Transduction);产热(Thermogenesis)

DOI 10.1371/journal.pbio.2006571

PMID 30653498

发布时间 2024-04-09

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Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.

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Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.

PLoS biology

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PLoS biology

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