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PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8<sup>+</sup> T-cell Function.

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第一作者： Sarah,Whelan

第一单位： Compugen, USA, Inc., South San Francisco, California.

作者： Sarah,Whelan ^[1] ; Eran,Ophir ^[2] ; Maya F,Kotturi ^[1] ; Ofer,Levy ^[2] ; Sudipto,Ganguly ^[3] ; Ling,Leung ^[1] ; Ilan,Vaknin ^[2] ; Sandeep,Kumar ^[1] ; Liat,Dassa ^[2] ; Kyle,Hansen ^[1] ; David,Bernados ^[1] ; Benjamin,Murter ^[3] ; Abha,Soni ^[3] ; Janis M,Taube ^[3] ; Amanda Nickles,Fader ^[4] ; Tian-Li,Wang ^[4] ; Ie-Ming,Shih ^[4] ; Mark,White ^[1] ; Drew M,Pardoll ^[3] ; Spencer C,Liang ^[5]

作者单位： Compugen, USA, Inc., South San Francisco, California. ^[1] Compugen Ltd, Holon, Israel. ^[2] Bloomberg Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, Maryland. ^[3] Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[4] Compugen, USA, Inc., South San Francisco, California. spencerl@cgen.com. ^[5]

医学主题词动物(Animals);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);淋巴细胞活化(Lymphocyte Activation);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);小鼠(Mice);肿瘤(Neoplasms);蛋白质结合(Protein Binding);受体, 细胞表面(Receptors, Cell Surface);受体, 免疫(Receptors, Immunologic);信号传导(Signal Transduction)

DOI 10.1158/2326-6066.CIR-18-0442

PMID 30659054

发布时间 2021-05-10

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Cancer immunology research

2019年7卷2期

257-268页

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Cancer immunology research

2019年7卷2期

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PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8<sup>+</sup> T-cell Function.

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PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8<sup>+</sup> T-cell Function.

Cancer immunology research

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Cancer immunology research

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