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首页> Gene> Cyclooxygenase-2 regulates HPS patient serum induced-directional collective HPMVEC migration via PKC/Rac signaling pathway.

Cyclooxygenase-2 regulates HPS patient serum induced-directional collective HPMVEC migration via PKC/Rac signaling pathway.

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作者： Xi,Tang ^[1] ; Chang,Liu ^[2] ; Lin,Chen ^[1] ; Zhiyong,Yang ^[1] ; Karine,Belguise ^[3] ; Xiaobo,Wang ^[3] ; Kaizhi,Lu ^[1] ; Hong,Yan ^[4] ; Bin,Yi ^[5]

作者单位： Department of Anaesthesia, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China. ^[1] Department of Anaesthesia, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China. ^[2] LBCMCP, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31062 Toulouse, France. ^[3] Department of Anaesthesia, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China. Electronic address: yhmzk1@126.com. ^[4] Department of Anaesthesia, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China. Electronic address: yibin1974@163.com. ^[5]

关键词 Angiogenesis Collective cell migration Cyclooxygenase-2 Hepatopulmonary syndrome Pulmonary vascular endothelial cells

主题词成年人(Adult);病例对照研究(Case-Control Studies);细胞运动(Cell Movement);细胞, 培养的(Cells, Cultured);环氧化酶1(Cyclooxygenase 1);地诺前列酮(Dinoprostone);内皮细胞(Endothelial Cells);内皮, 血管(Endothelium, Vascular);女(雌)性(Female);肝肺综合征(Hepatopulmonary Syndrome);人类(Humans);男(雄)性(Male);中年人(Middle Aged);新生血管化, 病理性(Neovascularization, Pathologic);磷酰化(Phosphorylation);蛋白激酶C(Protein Kinase C);血清(Serum);信号传导(Signal Transduction);rac GTP结合蛋白质类(rac GTP-Binding Proteins)

DOI 10.1016/j.gene.2019.01.009

PMID 30660713

发布时间 2019-03-05

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