换一批
换一批Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia.
作者：
Zhicheng,Shao [1]
;
Haneul,Noh [2]
;
Woong,Bin Kim [1]
;
Peiyan,Ni [3]
;
Christine,Nguyen [4]
;
Sarah E,Cote [1]
;
Elizabeth,Noyes [3]
;
Joyce,Zhao [1]
;
Teagan,Parsons [1]
;
James M,Park [1]
;
Kelvin,Zheng [1]
;
Joshua J,Park [1]
;
Joseph T,Coyle [3]
;
Daniel R,Weinberger [3]
;
Richard E,Straub [3]
;
Karen F,Berman [1]
;
Jose,Apud [5]
;
Dost,Ongur [5]
;
Bruce M,Cohen [6]
;
Donna L,McPhie [6]
;
Judith L,Rapoport [1]
;
Roy H,Perlis [1]
;
Thomas A,Lanz [1]
;
Hualin Simon,Xi [7]
;
Changhong,Yin [8]
;
Weihua,Huang [9]
;
Teruyoshi,Hirayama [10]
;
Emi,Fukuda [11]
;
Takeshi,Yagi [11]
;
Sulagna,Ghosh [12]
;
Kevin C,Eggan [13]
;
Hae-Young,Kim [12]
;
Leonard M,Eisenberg [12]
;
Alexander A,Moghadam [14]
;
Patric K,Stanton [14]
;
Jun-Hyeong,Cho [15]
;
Sangmi,Chung [16]
作者单位：
Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
[1]
Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, Fujian, China.
[2]
Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
[3]
Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA.
[4]
Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD, USA.
[5]
Clinical and Translational Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Intramural Research Program, Baltimore, MD, USA.
[6]
Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA.
[7]
Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, USA.
[8]
Internal Medicine Research Unit, Pfizer Inc., Cambridge, MA, USA.
[9]
Computational Sciences, Pfizer Inc., Cambridge, MA, USA.
[10]
Department of Pathology, New York Medical College, Valhalla, NY, USA.
[11]
KOKORO-Biology Group, Laboratories for Integrated Biology, Graduate School of Frontier Biosciences, Osaka University, Osaka Prefecture, Japan.
[12]
Department of Anatomy and Developmental Neurobiology, Tokushima University Graduate School of Medical Science, Tokushima, Japan.
[13]
Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.
[14]
Department of Public Health, New York Medical College, Valhalla, NY, USA.
[15]
New York Medical College/Westchester Medical Center Stem Cell Laboratory, Departments of Physiology and Medicine, New York Medical College, Valhalla, NY, USA.
[16]
Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA. juncho@ucr.edu.
[17]
Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA. schung8@nymc.edu.
[18]
Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA. schung8@nymc.edu.
[19]
主题词
动物(Animals);钙黏着糖蛋白类(Cadherins);女(雌)性(Female);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);中间神经元(Interneurons);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);额叶前皮质(Prefrontal Cortex);精神分裂症(Schizophrenia);信号传导(Signal Transduction);突触(Synapses)
DOI
10.1038/s41593-018-0313-z
PMID
30664768
发布时间
2021-12-04
- 浏览13
Nature neuroscience
Nature neuroscience
229-242页
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