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首页> The international journal of biochemistry & cell biology> B7-H3 is regulated by BRD4 and promotes TLR4 expression in pancreatic ductal adenocarcinoma.

B7-H3 is regulated by BRD4 and promotes TLR4 expression in pancreatic ductal adenocarcinoma.

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作者： Jingyuan,Zhao ^[1] ; Zibo,Meng ^[1] ; Chao,Xie ^[2] ; Chong,Yang ^[3] ; Zhiqiang,Liu ^[1] ; Shihong,Wu ^[1] ; Bo,Wang ^[1] ; Ping,Fan ^[1] ; Xin,Jin ^[4] ; Heshui,Wu ^[5]

作者单位： Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ^[1] Department of Hepatobiliary pancreatic surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. ^[2] Organ Transplantation Center, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, Sichuan, China. ^[3] Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: jinxinunion@hust.edu.cn. ^[4] Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: heshuiwu@hust.edu.cn. ^[5]

关键词 B7-H3 BET inhibitors BRD4 Pancreatic ductal adenocarcinoma (PDAC)TLR4

主题词细胞凋亡(Apoptosis);癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);核蛋白质类(Nuclear Proteins);信号传导(Signal Transduction);Toll样受体4(Toll-Like Receptor 4);转录因子(Transcription Factors)

DOI 10.1016/j.biocel.2019.01.011

PMID 30664982

发布时间 2019-12-10

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The international journal of biochemistry & cell biology

84-91页

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