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首页> Thrombosis and haemostasis> Long-Term Treatment with Thrombomodulin Improves Functional Outcomes after Cerebral Ischemia Even if Administration is Delayed.

Long-Term Treatment with Thrombomodulin Improves Functional Outcomes after Cerebral Ischemia Even if Administration is Delayed.

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作者： Takafumi,Nakano ^[1] ; Yoshihiko,Nakamura ^[2] ; Kiyoshi,Matsuyama ^[3] ; Keiichi,Irie ^[4] ; Mako,Yasumura ^[5] ; Yurie,Hirata ^[2] ; Motoki,Yamasaki ^[2] ; Kanae,Misumi ^[5] ; Yuta,Yamashita ^[2] ; Takayuki,Myose ^[4] ; Koichi,Matsuo ^[2] ; Kazunori,Sano ^[2] ; Hidetoshi,Kamimura ^[1] ; Hiroyasu,Ishikura ^[2] ; Takashi,Egawa ^[1] ; Kenichi,Mishima ^[3]

作者单位： Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Jyonan, Fukuoka, Japan. ^[1] Department of Pharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Jyonan, Fukuoka, Japan. ^[2] Department of Pharmacy, Fukuoka University Hospital, Jonan, Fukuoka, Japan. ^[3] Department of Emergency and Critical Care Medicine, Fukuoka University Hospital, Jonan, Fukuoka, Japan. ^[4] Department of Biochemistry and Applied Chemistry, Kurume National College of Technology, Kurume, Japan. ^[5]

主题词动物(Animals);血液凝固(Blood Coagulation);脑(Brain);疾病模型, 动物(Disease Models, Animal);用药计划表(Drug Administration Schedule);HMGB1蛋白质(HMGB1 Protein);梗死, 大脑中动脉(Infarction, Middle Cerebral Artery);注射, 腹腔内(Injections, Intraperitoneal);男(雄)性(Male);小鼠(Mice);小神经胶质细胞(Microglia);运动活动(Motor Activity);重组蛋白质类(Recombinant Proteins);旋转棒性能试验(Rotarod Performance Test);血栓调节蛋白(Thrombomodulin);时间因素(Time Factors);增量调节(Up-Regulation)

DOI 10.1055/s-0038-1677532

PMID 30665239

发布时间 2019-07-08

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Thrombosis and haemostasis

Thrombosis and haemostasis

2019年119卷3期

467-478页

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